Publications
Selected recent and landmark work
Explore work spanning mutation-specific TP53 biology, p53 isoforms, YB-1, genomic instability, RNA processing, metastasis and translational cancer genomics.
YBX1 Expression Marks Proliferative Tumour States with Context-Dependent Genomic Instability: A Pan-Cancer Analysis
International Journal of Molecular Sciences
TP53 mutation at codon 179 metabolically reprograms cancer cells to promote invasion
Cancer Gene Therapy
TP53 Splice Mutations Have Tumour-Independent Effects on Genomic Stability and Prognosis: An In Silico Study
International Journal of Molecular Sciences
Combining TP53 mutation and isoform has the potential to improve clinical practice
Pathology
Increased Expression of the Δ133p53β Isoform Enhances Brain Metastasis
International Journal of Molecular Sciences
Impact of Clinical Data Veracity on Cancer Genomic Research
JNCI Cancer Spectrum
Adaptive homeostasis and the p53 isoform network
EMBO Reports
Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells
Nature Communications
Breast cancer patient prognosis is determined by the interplay between TP53 mutation and alternative transcript expression: Insights from TP53 long amplicon digital PCR assays
Cancers
Critical Role for Cold Shock Protein YB-1 in Cytokinesis
Cancers
Dephosphorylation of YB-1 is Required for Nuclear Localisation During G2 Phase of the Cell Cycle
Cancers
A Study of TP53 RNA Splicing Illustrates Pitfalls of RNA-seq Methodology
Cancer Research